Trabajos publicados

A continuación se incluyen algunos de nuestros trabajos publicados en revistas científicas internacionales y asistencia a congresos. Puedes acceder a la fuente original haciendo clic sobre la imagen o contactando con nosotros.

Artículo científico

Electroencefalografía Cuantitativa como herramienta para el diagnóstico y seguimiento del paciente con trastorno por déficit de atención/hiperactividad

Adrián Galiana-Simal; Pilar Vecina-Navarro; Prado Sánchez Ruiz; María Vela-Romero.

Quantitative electroencephalography as a tool for the diagnosis and follow-up of patients with attention-deficit/hyperactivity disorder.

Revista de Neurología. 2020;70:197-205.

Abstract
INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) diagnosis is based on behavioral symptoms referred by the patient or their caregivers, which includes a high subjective component. This highlights the need to find biomarkers that might help clinicians to objectively identify this condition and to assess the evolution of the patient and the effectiveness of the treatments using quantitative information. Previous studies suggest that data from quantitative electroencephalography (qEEG) could be useful for the diagnosis and follow-up of patients with ADHD; however, many professionals do not know its possibilities. AIMS: To describe and discuss the principal findings of qEEG neurometry in ADHD subjects along the last 10 years. PATIENTS AND METHODS: A systematic review, based on PRISMA methodology and using PubMed database, was carried out to identify original articles published in the last 10 years, that studied qEEG parameters within the ADHD context. RESULTS: A total of 13 research articles out of 65 were selected for an in-depth analysis. CONCLUSIONS: qEEG parameters could provide relevant information in the context of ADHD; however, its applicability is currently limited to complementing the subjective diagnosis methods and not to its replacement, as published data are just preliminary and need larger and deeper studies. However, qEEG data can help to better understand ADHD and its neurophysiology, characterize its subtypes and therefore move towards personalized and more effective treatments.

Artículo científico

Trastorno del procesamiento sensorial: puntos clave de una alteración frecuente en los trastornos del neurodesarrollo

Adrián Galiana-Simal; María Vela-Romero; Víctor M. Romero-Vela; Nuria Oliver-Tercero; Virginia García-Olmo; Pedro Javier Benito-Castellanos; Victoria Muñoz-Martínez; Luis Beato-Fernández.

Sensory processing disorder: Key points of a frequent alteration in neurodevelopmental disorders.

Cogent Medicine. 2020;7:1-12.

Abstract
Altered neurological sensory integration results in Sensory Processing Disorder (SPD), also known as Sensory Regulation Dysfunction, Sensory Integration Dysfunction or Sensory Dysfunction Disorder. Under this condition, the brain doesn’t process sensory inputs correctly, following inappropriate behavioral and motor responses that affect learning, coordination, behavior and language. SPD may lead to stress, anxiety or even depression, and represents a risk of psychopathology. Epidemiological studies carried out in western lifestyle populations have shown a high prevalence of SPD among children (5-15%); however, a large number of health professionals still do not know this condition, giving rise to unattended children and frustrated families. This review aims to provide an updated starting point about some of the most relevant aspects of SPD.


Artículo científico

Hacia un futuro diagnóstico molecular del autismo: avances recientes en investigación sobre biomarcadores procedentes de muestras de saliva

Adrián Galiana-Simal; Victoria Muñoz-Martínez; Paloma Calero-Bueno; María Vela-Romero; Luis Beato-Fernández

Towards a future molecular diagnosis of autism: Recent advances in biomarkers research from saliva samples.

International Journal of Developmental Neuroscience. 2018;67:1-5.

Abstract
Autism spectrum disorder diagnosis is currently based on clinical observations and behavioral evaluations exclusively, without any biological determination. Molecular biomarkers are usually obtained from biological fluids, such as blood or urine, generally through invasive and uncomfortable procedures. Patients with autism are characterized by sensory reactivity and behavioral difficulties which make sample collection problematic. Saliva has emerged as a feasible alternative to obtain relevant biological information and is especially indicated in the case of children with autism due to its painless and noninvasive sampling characteristics. Furthermore, saliva represents a valuable resource to study candidate biomarkers of autism. This has resulted in a number of interesting studies reported during the last 5 years that we have gathered and briefly discussed.

Artículo científico

Conectando los trastornos de la conducta alimentaria con el trastorno del procesamiento sensorial: una hipótesis sensorio-alimentaria

Adrián Galiana-Simal; Victoria Muñoz-Martínez; Luis Beato-Fernández.

Connecting Eating Disorders and Sensory Processing Disorder: A Sensory Eating Disorder Hypothesis.

Glob Jour Intell Develop Dis. 2017;3:1-2.

Abstract
Eating disorders are pathological conditions characterized by disturbed eating behaviors that affect mental and physical health. Among them, some Avoidant-Restrictive Food Intake Disorder (ARFID), Pica and Anorexia Nervosa (AN) studies have shown, at least in part, a sensory-related etiology. Sensory Processing Disorder (SPD) is a neurological condition that exists when the brain has an altered processing of sensory signals, resulting in non-adaptive motor and/or behavioral responses. Some of the SPD phenotypes include hyper or hypo-reactivity to one or more sensory channels, including tactile, olfactory, visual and oral that might have connections with the aforementioned eating disorders, like atypical responses from determined food colors, textures or smells which eventually lead to unhealthy eating behaviors, weight imbalance, malnutrition and psychosocial impairment. We have gathered and discussed some of the most relevant studies about the connection between eating disorders and SPD, proposing a general term called sensory eating disorder to define peculiar SPD cases that might evolve to an established eating disorder.

Artículo científico

Las adaptaciones en el entorno mejoran la percepción de la accesibilidad cognitiva en los adultos jóvenes con trastorno del espectro autista

María Vela-Romero; Pedro Javier Benito-Castellanos; Adrián Galiana-Simal

Environmental modification improves perception of cognitive accessibility in young adults with autism.

RetoCyL. 2016;7.

Abstract
Active participation, autonomy, occupational performance and self-determination depend in part on environmental conditions and accessibility. The present study evaluates how environmental cognitive barriers can be reduced trough proper modifcations. We have developed a new test to measure how an individual perceives changes on cognitive accessibility in natural environments (CANE). 12 young adult males with 23-34 years old were divided in 2 groups: autism spectrum disorder group (ASD, n=4) and control group with no mental disorders (NO-ASD, n=8). CANE test was applied to all participants in 3 different natural environments before and after improving visual information and signage on each environment. Data analysis revealed that both ASD and NO-ASD individuals perceived a more comfortable and accessible environment after their modifcation.. In conclusion, simple environmental modifcations can highly increase how ASD people perceive and integrate signals to improve their daily autonomy, generating a path towards equity and the Desing for All.